Ausgewählte Publikationen

Wiegand C, Fink S, Mogrovejo DC, Ruhlandt M, Wiencke V, Eberlein T, Brill FHH, Tittelbach J. A standardized wound infection model for antimicrobial testing of wound dressings in vitroInt Wound J. 2024(3):e14811. doi: 10.1111/iwj.14811.

Wiegand C, Dirksen A, Tittelbach J. Treatment with a red-laser-based wound therapy device exerts positive effects in models of delayed keratinocyte and fibroblast wound healing Photodermatol Photoimmunol Photomed. 2024 (1):e12926. doi: 10.1111/phpp.12926.

Riedl R, Kühn A, Rietz D, Hebecker B, Glowalla KG, Peltner LK, Jordan PM, Werz O, Lorkowski S, Wiegand C, Wallert M. Establishment and Characterization of Mild Atopic Dermatitis in the DNCB-Induced Mouse Model. Int J Mol Sci. 2023  24(15):12325. doi: 10.3390/ijms241512325 

Trodtfeld F, Tölke T, Wiegand C. Developing a Prolamin-Based Gel for Food Packaging: In-Vitro Assessment of Cytocompatibility. Gels. 2023 9(9):740. doi: 10.3390/gels9090740.

Riedl R, Kühn A, Hupfer Y, Hebecker B, Peltner LK, Jordan PM, Werz O, Lorkowski S, Wiegand C, Wallert M. Characterization of Different Inflammatory Skin Conditions in a Mouse Model of DNCB-Induced Atopic Dermatitis Inflammation. 2023. doi: 10.1007/s10753-023-01943-x.

Nenoff P, Stahl M, Schaller M, Burmester A, Monod M, Ebert A, Uhrlaß S. [Recurrent tinea corporis generalisata due to Terbinafine-resistant Trichophyton rubrum strain : Long-term treatment with super bioavailability itraconazole] Dermatologie 2023 74(11):864-873. doi: 10.1007/s00105-023-05232-4.

Winter P, Burmester A, Tittelbach J, Wiegand C. A New Genotype of Trichophyton quinckeanum with Point Mutations in Erg11A Encoding Sterol 14-α Demethylase Exhibits Increased Itraconazole Resistance. J. Fungi. 2023, 9, 1006. doi.org/10.3390/jof9101006

Morgner B, Tittelbach J, Wiegand C. Induction of psoriasis- and atopic dermatitis-like phenotypes in 3D skin equivalents with a fibroblast-derived matrix. Sci Rep. 2023 Jan 31;13(1):1807. doi: 10.1038/s41598-023-28822-7.

Riedl R, Wallert M, Lorkowski S, Wiegand C. Effects of Histamine and the α-Tocopherol Metabolite α-13'-COOH in an Atopic Dermatitis Full-Thickness Skin Model. Molecules. 2023 Jan 3;28(1):440. doi: 10.3390/molecules28010440.

Fink S, Fischer M, Spange S, Beier O, Horn K, Tittelbach J, Wiegand C. Cold Atmospheric Plasma Exerts Antimicrobial Effects in a 3D Skin Model of Cutaneous Candidiasis. Antibiotics (Basel). 2023 May 19;12(5):933. doi: 10.3390/antibiotics12050933.

Andriessen A, Wiegand C, Eberlein T, Erfurt-Berge C, Roes C. Clinical Experience Using a Monofilament Fiber Cleansing and Debriding Technology for Various Skin Conditions. J Drugs Dermatol. 2022 Nov 1;21(11):1173-1180. doi: 10.36849/JDD.6261.

Reddersen K, Tittelbach J, Wiegand C. 3D Biofilm Models Containing Multiple Species for Antimicrobial Testing of Wound Dressings. Microorganisms. 2022 Oct 13;10(10):2027. doi: 10.3390/microorganisms10102027.

Trodtfeld F, Tölke T, Wiegand C. Antimicrobial Functionalization of Prolamine-Silica Hybrid Coatings with Fumaric Acid for Food Packaging Materials and Their Biocompatibility. Antibiotics (Basel). 2022 Sep 16;11(9):1259. doi: 10.3390/antibiotics11091259.

Morgner B, Husmark J, Arvidsson A, Wiegand C. Effect of a DACC-coated dressing on keratinocytes and fibroblasts in wound healing using an in vitro scratch model. J Mater Sci Mater Med. 2022 Feb 8;33(2):22. doi: 10.1007/s10856-022-06648-5.

Fink S, Sethmann A, Hipler UC, Wiegand C. In vitro investigation of the principle of action of ammonium bituminosulfonate ointments on a 3D skin model. Eur J Pharm Sci. 2022 May 1;172:106152. doi: 10.1016/j.ejps.2022.106152.

Husmark J, Morgner B, Susilo YB, Wiegand C. Antimicrobial effects of bacterial binding to a dialkylcarbamoyl chloride-coated wound dressing: an in vitro study. J Wound Care. 2022 Jul 2;31(7):560-570. doi: 10.12968/jowc.2022.31.7.560.

Bellmann T, Luber R, Kischio L, Karl B, Pötzinger Y, Beekmann U, Kralisch D, Wiegand C, Fischer D. Bacterial nanocellulose patches as a carrier for hydrating formulations to improve the topical treatment of nail diseases. Int J Pharm. 2022 Nov 25;628:122267. doi: 10.1016/j.ijpharm.2022.122267.

Burmester A, Hipler UC, Elsner P, Wiegand C. Point mutations in the squalene epoxidase erg1 and sterol 14-α demethylase erg11 gene of T indotineae isolates indicate that the resistant mutant strains evolved independently. Mycoses. 2022 Jan;65(1):97-102. doi: 10.1111/myc.13393.

Fink S, Burmester A, Hipler UC, Neumeister C, Götz MR, Wiegand C. Efficacy of antifungal agents against fungal spores: An in vitro study using microplate laser nephelometry and an artificially infected 3D skin model. Microbiologyopen. 2022 Feb;11(1):e1257. doi: 10.1002/mbo3.1257.

Tasar R, Wiegand C, Elsner P. How irritant are n-propanol and isopropanol? - A systematic review. Contact Dermatitis. 2021 Jan;84(1):1-14. doi: 10.1111/cod.13722.

Gregersen DM, Burmester A, Ludriksone L, Darr-Foit S, Hipler C, Wiegand C. Renaissance des Mäusefavus : Retrospektive Analyse der Trichophyton-quinckeanum-Infektionen am Universitätsklinikum Jena im Zeitraum 2015 bis 2020 [Renaissance of mouse favus : Retrospective analysis of Trichophyton quinckeanum infections at Jena University Hospital in the period 2015-2020]. Hautarzt. 2021 Oct;72(10):847-854. German. doi: 10.1007/s00105-021-04876-4.

Reddersen K, Güllmar A, Tonndorf-Martini S, Sigusch BW, Ewald A, Dauben TJ, Martin K, Wiegand C. Critical parameters in cultivation of experimental biofilms using the example of Pseudomonas fluorescens. J Mater Sci Mater Med. 2021 Aug 18;32(9):96. doi: 10.1007/s10856-021-06568-w.

Sliwiak P, Folwarczny E, Didona D, Fink S, Wiegand C, Hanschmann EM, Hertl M, Hudemann C. Redox Enzymes of the Thioredoxin Family as Potential and Novel Markers in Pemphigus. Oxid Med Cell Longev. 2021 Apr 1;2021:6672693. doi: 10.1155/2021/6672693.

Wiegand C, Hipler UC, Elsner P, Tittelbach J. Keratinocyte and Fibroblast Wound Healing In Vitro Is Repressed by Non-Optimal Conditions but the Reparative Potential Can Be Improved by Water-Filtered Infrared A. Biomedicines. 2021 Nov 30;9(12):1802. doi: 10.3390/biomedicines9121802.

Moelleken M, Jockenhöfer F, Wiegand C, Buer J, Benson S, Dissemond J. Pilotstudie zum Einfluss von kaltem atmosphärischem Plasma auf bakterielle Kontamination und Heilungstendenz chronischer Wunden. J Dtsch Dermatol Ges. 2020 Oct;18(10):1094-1102. German. doi: 10.1111/ddg.14294_g.

Fink S, Reddersen K, Wiegand C, Elsner P, Hipler UC. Evaluation of cell and hemocompatibility of Cucurbiturils. Eur J Pharm Sci. 2020 Apr 15;146:105271. doi: 10.1016/j.ejps.2020.105271.

Reddersen K, Greber KE, Korona-Glowniak I, Wiegand C. The Short Lipopeptides (C10)2-KKKK-NH2 and (C12)2-KKKK-NH2 Protect HaCaT Keratinocytes from Bacterial Damage Caused by Staphylococcus aureus Infection in a Co-Culture Model. Antibiotics (Basel). 2020 Dec 8;9(12):879. doi: 10.3390/antibiotics9120879.

Reddersen K, Burmester A, Dieckmeyer C, Engelmann C, Goetze S, Gregersen D, Hipler UC, Ludriksone L, Peckruhn M, Schliemann S, Tittelbach J, Wiegand C, Elsner P. 95 Jahre Universitäts-Hautklinik Jena: Geschichte und Gegenwart. Akt Dermatol 2020; 46: 322–329. German. doi: 10.1055/a-1038-6339.

Beekmann U, Zahel P, Karl B, Schmölz L, Börner F, Gerstmeier J, Werz O, Lorkowski S, Wiegand C, Fischer D, Kralisch D. Modified Bacterial Cellulose Dressings to Treat Inflammatory Wounds. Nanomaterials (Basel). 2020 Dec 14;10(12):2508. doi: 10.3390/nano10122508.

Schumny U, Wiegand C, Hipler UC, Darr-Foit S, Peckruhn M, Uhrlaß S, Nenoff P, Elsner P. Berufliche Infektion mit Trichophyton verrucosum bei einem Rinderzüchter [Occupational Trichophyton verrucosum infection in a cattle farmer]. Hautarzt. 2020 Nov;71(11):899-902. German. doi: 10.1007/s00105-020-04655-7.

Ebert A, Monod M, Salamin K, Burmester A, Uhrlaß S, Wiegand C, Hipler UC, Krüger C, Koch D, Wittig F, Verma SB, Singal A, Gupta S, Vasani R, Saraswat A, Madhu R, Panda S, Das A, Kura MM, Kumar A, Poojary S, Schirm S, Gräser Y, Paasch U, Nenoff P. Alarming India-wide phenomenon of antifungal resistance in dermatophytes: A multicentre study. Mycoses. 2020 Jul;63(7):717-728. doi: 10.1111/myc.13091.

Hesse-Macabata J, Morgner B, Elsner P, Hipler UC, Wiegand C. Tryptanthrin promotes keratinocyte and fibroblast responses in vitro after infection with Trichophyton benhamiae DSM6916. Sci Rep. 2020 Feb 5;10(1):1863. doi: 10.1038/s41598-020-58773-2.

Burmester A, Hipler UC, Uhrlaß S, Nenoff P, Singal A, Verma SB, Elsner P, Wiegand C. Indian Trichophyton mentagrophytes squalene epoxidase erg1 double mutants show high proportion of combined fluconazole and terbinafine resistance. Mycoses. 2020 Jul 29. doi: 10.1111/myc.13150.

Warncke P, Fink S, Wiegand C, Hipler UC, Fischer D. A shell-less hen's egg test as infection model to determine the biocompatibility and antimicrobial efficacy of drugs and drug formulations against Pseudomonas aeruginosa. Int J Pharm. 2020 Jul 30;585:119557. doi: 10.1016/j.ijpharm.2020.119557.

Moelleken M, Jockenhöfer F, Wiegand C, Buer J, Benson S, Dissemond J. Pilot study on the influence of cold atmospheric plasma on bacterial contamination and healing tendency of chronic wounds. J Dtsch Dermatol Ges. 2020 Oct;18(10):1094-1101. doi: 10.1111/ddg.14294.

Gamage H, Sivanesan P, Hipler UC, Elsner P, Wiegand C. Superficial fungal infections in the department of dermatology, University Hospital Jena: A 7-year retrospective study on 4556 samples from 2007 to 2013. Mycoses. 2020 Jun;63(6):558-565. doi: 10.1111/myc.13077.

Pothmann A, Illing T, Wiegand C, Hartmann AA, Elsner P. The Microbiome and Atopic Dermatitis: A Review. Am J Clin Dermatol. 2019 Dec;20(6):749-761. doi: 10.1007/s40257-019-00467-1.

Wiegand C, Burmester A, Tittelbach J, Darr-Foit S, Goetze S, Elsner P, Hipler UC. Dermatophytosen, verursacht durch seltene anthropophile und zoophile Erreger [Dermatophytosis caused by rare anthropophilic and zoophilic agents]. Hautarzt. 2019 Aug;70(8):561-574. German. doi: 10.1007/s00105-019-4429-1.

Wiegand C, Abel M, Hipler UC, Elsner P, Zieger M, Kurz J, Wendel HP, Stoppelkamp S. Hemostatic wound dressings: Predicting their effects by in vitro tests. J Biomater Appl. 2019 Apr;33(9):1285-1297. doi: 10.1177/0885328219831095.

Eberlein T, Wiegand C, Andriessen A, Roes C, Abel M. Use of a monofilament debridement pad in the treatment of acne vulgaris. J Wound Care. 2019 Nov 2;28(11):780-783. doi: 10.12968/jowc.2019.28.11.780.

Nenoff P, Verma SB, Vasani R, Burmester A, Hipler UC, Wittig F, Krüger C, Nenoff K, Wiegand C, Saraswat A, Madhu R, Panda S, Das A, Kura M, Jain A, Koch D, Gräser Y, Uhrlaß S. The current Indian epidemic of superficial dermatophytosis due to Trichophyton mentagrophytes-A molecular study. Mycoses. 2019 Apr;62(4):336-356. doi: 10.1111/myc.12878.

Wiegand C, Abel M, Hipler UC, Elsner P. Effect of non-adhering dressings on promotion of fibroblast proliferation and wound healing in vitro. Sci Rep. 2019 Mar 13;9(1):4320. doi: 10.1038/s41598-019-40921-y.

Kschonsek J, Wiegand C, Hipler UC, Böhm V. Influence of polyphenolic content on the in vitro allergenicity of old and new apple cultivars: A pilot study. Nutrition. 2019 Feb;58:30-35. doi: 10.1016/j.nut.2018.07.001.

Reddersen K, Wiegand C, Elsner P, Hipler UC. Three-dimensional human skin model infected with Staphylococcus aureus as a tool for evaluation of bioactivity and biocompatibility of antiseptics. Int J Antimicrob Agents. 2019 Sep;54(3):283-291. doi: 10.1016/j.ijantimicag.2019.06.022.

Hesse-Macabata J, Morgner B, Morgenstern S, Grimm MO, Elsner P, Hipler UC, Wiegand C. Innate immune response of human epidermal keratinocytes and dermal fibroblasts to in vitro incubation of Trichophyton benhamiae DSM 6916. J Eur Acad Dermatol Venereol. 2019 Jun;33(6):1177-1188. doi: 10.1111/jdv.15472.

Burmester A, Hipler UC, Hensche R, Elsner P, Wiegand C. Point mutations in the squalene epoxidase gene of Indian ITS genotype VIII T. mentagrophytes identified after DNA isolation from infected scales. Med Mycol Case Rep. 2019 Sep 18;26:23-24. doi: 10.1016/j.mmcr.2019.09.001.

Burmester A, Hipler UC, Elsner P, Wiegand C. Mating analyses of Trichophyton benhamiae offspring reveals linkage of genetic markers used in taxonomy. Med Mycol. 2019 Oct 1;57(7):885-892. doi: 10.1093/mmy/myy141.

Antonov D, Wiegand C, Schliemann S, Elsner P. Segmentaler Morbus Darier mit ungewöhnlich spätem Beginn. J Dtsch Dermatol Ges. 2018 Nov;16(11):1365-1367. doi: 10.1111/ddg.13674_g.

Silge A, Heinke R, Bocklitz T, Wiegand C, Hipler UC, Rösch P, Popp J. The application of UV resonance Raman spectroscopy for the differentiation of clinically relevant Candida species. Anal Bioanal Chem. 2018 Sep;410(23):5839-5847. doi: 10.1007/s00216-018-1196-2.

Wollina U, Wiegand C, Hipler UC. Calcium hydroxylapatite microspheres – biocompatibility and clinical effects. Georgian Med News. 2018 May;(278):62-68.

Wiegand C, Völpel A, Ewald A, Remesch M, Kuever J, Bauer J, Griesheim S, Hauser C, Thielmann J, Tonndorf-Martini S, Sigusch BW, Weisser J, Wyrwa R, Elsner P, Hipler UC, Roth M, Dewald C, Lüdecke-Beyer C, Bossert J. Critical physiological factors influencing the outcome of antimicrobial testing according to ISO 22196 / JIS Z 2801. PLoS One. 2018 Mar 20;13(3):e0194339. doi: 10.1371/journal.pone.0194339.

Wiegand C, Fink S, Hipler UC, Beier O, Horn K, Pfuch A, Schimanski A, Grünler B. Cold atmospheric pressure plasmas exhibit antimicrobial properties against critical bacteria and yeast species. J Wound Care. 2017 Aug 2;26(8):462-468. doi: 10.12968/jowc.2017.26.8.462.

Wiegand C, Bittenger K, Galiano RD, Driver VR, Gibbons GW. Does noncontact low-frequency ultrasound therapy contribute to wound healing at the molecular level? Wound Repair Regen. 2017 Sep;25(5):871-882. doi: 10.1111/wrr.12595.

McNamara RK, Szeszko PR, Smesny S, Ikuta T, DeRosse P, Vaz FM, Milleit B, Hipler UC, Wiegand C, Hesse J, Amminger GP, Malhotra AK, Peters BD. Polyunsaturated fatty acid biostatus, phospholipase A2 activity and brain white matter microstructure across adolescence. Neuroscience. 2017 Feb 20;343:423-433. doi: 10.1016/j.neuroscience.2016.12.007.

Eberhardt K, Matthäus C, Winter D, Wiegand C, Hipler UC, Diekmann S, Popp J. Raman and infrared spectroscopy differentiate senescent from proliferating cells in a human dermal fibroblast 3D skin model. Analyst. 2017 Nov 20;142(23):4405-4414. doi: 10.1039/c7an00592j.

Wiegand C, Eberlein T, Andriessen A. Antibacterial activity of polihexanide formulations in a co-culture of HaCaT keratinocytes and Staphylococcus aureus and at different pH levels. Wound Repair Regen. 2017 May;25(3):423-431. doi: 10.1111/wrr.12528.

Wiegand C, Mugisha P, Mulyowa GK, Elsner P, Hipler UC, Gräser Y, Uhrlaß S, Nenoff P. Identification of the causative dermatophyte of tinea capitis in children attending Mbarara Regional Referral Hospital in Uganda by PCR-ELISA and comparison with conventional mycological diagnostic methods. Med Mycol. 2017 Aug 1;55(6):660-668. doi: 10.1093/mmy/myw112.

Eberlein T, Wiegand C, Brill FH. According to the Article "Cytokine Expression in Human Osteoblasts After Antiseptic Treatment: A Comparative Study between Polyhexanide and Chlorhexidine" by Röhner E. et al., Journal of Investigative Surgery, 28, 1-7, 2015. J Invest Surg. 2017 Feb;30(1):66-67. doi: 10.1080/08941939.2016.1254307.

Wiegand C, Bauer A, Brasch J, Nenoff P, Schaller M, Mayser P, Hipler UC, Elsner P. Are the classic diagnostic methods in mycology still state of the art? J Dtsch Dermatol Ges. 2016 May;14(5):490-4. doi: 10.1111/ddg.12980.

Wiegand C, Mugisha P, Mulyowa GK, Elsner P, Hipler UC, Gräser Y, Uhrlaß S, Nenoff P. Trichophyton violaceum : Haupterreger der Tinea capitis bei Kindern im Mbarara Regional Referral Hospital in Uganda [Trichophyton violaceum : Main cause of tinea capitis in children at Mbarara Regional Referral Hospital in Uganda]. Hautarzt. 2016 Sep;67(9):712-7. German. doi: 10.1007/s00105-016-3831-1.

Reddersen K, Finger S, Zieger M, Wiegand C, Buschmann HJ, Elsner P, Hipler UC. Cytocompatibility testing of cyclodextrin-functionalized antimicrobial textiles-a comprehensive approach. J Mater Sci Mater Med. 2016 Dec;27(12):190. doi: 10.1007/s10856-016-5804-4.

Ganske K, Wiegand C, Hipler UC, Heinze T. Synthesis of Novel Cellulose Carbamates Possessing Terminal Amino Groups and Their Bioactivity. Macromol Biosci. 2016 Mar;16(3):451-61. doi: 10.1002/mabi.201500324.

Wiegand C, Buhren BA, Bünemann E, Schrumpf H, Homey B, Frykberg RG, Lurie F, Gerber PA. A novel native collagen dressing with advantageous properties to promote physiological wound healing. J Wound Care. 2016 Dec 2;25(12):713-720. doi: 10.12968/jowc.2016.25.12.713.

Hiernickel C, Wiegand C, Schliemann S, Seyfarth F, Jung K, Elsner P, Hipler UC. Trichophyton Spezies von Arthroderma benhamiae: Klinisch therapeutische Aspekte eines neuen Erregers in der Dermatologie [Trichophyton species of Arthroderma benhamiae : Clinical therapeutic aspects of a new pathogen in dermatology]. Hautarzt. 2016 Sep;67(9):706-11. German. doi: 10.1007/s00105-016-3837-8.

Wiegand C, Fink S, Beier O, Horn K, Pfuch A, Schimanski A, Grünler B, Hipler UC, Elsner P. Dose- and Time-Dependent Cellular Effects of Cold Atmospheric Pressure Plasma Evaluated in 3D Skin Models. Skin Pharmacol Physiol. 2016;29(5):257-265. doi: 10.1159/000450889.

Wiegand C, Reddersen K, Hipler UC, Abel M, Ruth P, Andriessen A. In vitro Evaluation of the Cleansing Effect of a Monofilament Fiber Debridement Pad Compared to Gauze Swabs. Skin Pharmacol Physiol. 2016;29(6):318-323. doi: 10.1159/000454720.

Wiegand C, Abel M, Ruth P, Elsner P, Hipler UC. pH influence on antibacterial efficacy of common antiseptic substances. Skin Pharmacol Physiol. 2015;28(3):147-58. doi: 10.1159/000367632.

Wiegand C, Moritz S, Hessler N, Kralisch D, Wesarg F, Müller FA, Fischer D, Hipler UC. Antimicrobial functionalization of bacterial nanocellulose by loading with polihexanide and povidone-iodine. J Mater Sci Mater Med. 2015 Oct;26(10):245. doi: 10.1007/s10856-015-5571-7.

Spange S, Pfuch A, Wiegand C, Beier O, Hipler UC, Grünler B. Atmospheric pressure plasma CVD as a tool to functionalise wound dressings. J Mater Sci Mater Med. 2015 Feb;26(2):76. doi: 10.1007/s10856-015-5417-3.

Zieger M, Wurlitzer M, Wiegand C, Reddersen K, Finger S, Elsner P, Laudeley P, Liebert T, Heinze T, Hipler UC. 6-Deoxy-6-aminoethyleneamino cellulose: synthesis and study of hemocompatibility. J Biomater Sci Polym Ed. 2015;26(14):931-46. doi: 10.1080/09205063.2015.1068546.

Wiegand C, Abel M, Ruth P, Elsner P, Hipler UC. In vitro assessment of the antimicrobial activity of wound dressings: influence of the test method selected and impact of the pH. J Mater Sci Mater Med. 2015 Jan;26(1):5343. doi: 10.1007/s10856-014-5343-9.

Smesny S, Milleit B, Schaefer MR, Hipler UC, Milleit C, Wiegand C, Hesse J, Klier CM, Holub M, Holzer I, Berk M, McGorry PD, Sauer H, Amminger GP. Effects of omega-3 PUFA on the vitamin E and glutathione antioxidant defense system in individuals at ultra-high risk of psychosis. Prostaglandins Leukot Essent Fatty Acids. 2015 Oct;101:15-21. doi: 10.1016/j.plefa.2015.07.001.

Wiegand C, Nikolajski M, Hipler UC, Heinze T. Nanoparticle Formulation of AEA and BAEA Cellulose Carbamates Increases Biocompatibility and Antimicrobial Activity. Macromol Biosci. 2015 Sep;15(9):1242-51. doi: 10.1002/mabi.201500031.